2021.10.26 23:57 magazinethekid Solo Mission | Let's Play Specter! #3
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2021.10.26 23:57 juicyhorchata please let me know what you guys thought about S. 4 Ep. 18 “Won’t You Pimai Neighbor”
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2021.10.26 23:57 JobHunter2019-20 Need to have conversations about life altering decisions or issues with powers? Talk to this random chap who now is your bff!
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2021.10.26 23:57 Accomplished_Bat_893 Carry handle rail
When I posted my sorta retro AR, there was a comment linking to where to buy authentic period correct rails for like 50 bucks a pop. I can't find that comment anymore.
Does anyone know what I'm talking about?
submitted by Accomplished_Bat_893 to RetroAR [link] [comments]
2021.10.26 23:57 master0fcats uber availability?
hey y'all! i'll be coming into new orleans for the next few days and was wondering what the ride situation is currently like. in Vegas in June they were readily available and not TOO pricey; in Chicago last month, going ten minutes away cost you like $65. just wondering if my normal budget for a ride will be enough or if i need to be prepared for things to be insane. also aware it's Halloween weekend so I know surge pricing will be a thing, but will it be as bad as $65 a ride? TIA! Haven't been back to New Orleans in like 6 years and am very excited.
submitted by master0fcats to AskNOLA [link] [comments]
2021.10.26 23:57 Shaitan87 Ignition Hackathon results
Hi, has anyone found a list of the winners of the hackathon?
I read they were supposed to be announced on the 25th, but I haven't been able to find out more than that.
submitted by Shaitan87 to solana [link] [comments]
2021.10.26 23:57 luka_ruka Fixed it
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2021.10.26 23:57 daSynth How tf is lotp still not out
2021.10.26 23:57 ClayDesk How IQ and Intelligence Affect Our Life or Not! Must watch!
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2021.10.26 23:57 shaunshawnSHAWN Where is Carpal Tunnel Hero 2? I saw a video for it today and I'd like to give it a go
2021.10.26 23:57 tootsie404 Favorite popcorn seasonings!
2021.10.26 23:57 _ezpzlemonsqueezy How to add image to email signature gmail
I’m using gmail trying to add a small logo image to my signature:
I tried just clicking the insert image button but when I send the image it sends as a blank box. Through searching, people are saying not to use that button and to use html. I’ve tried using this:
and replacing the link with the google drive image link but not working and just showing the text.
Does anyone know what to do? Thanks
submitted by _ezpzlemonsqueezy to smallbusiness [link] [comments]
2021.10.26 23:57 Dangsta_03 To the people who are saying what he did wasnt that bad
I think what he did was pretty shitty, but it can be forgiven, however i think there is a lot more then what was mentioned
Eddys tweet and him saying “Talking to Sabrina I don’t think I had a grasp on the kind of relationship they had privately” like fucking hell, that does not sound good at all.
I think Sabrina made that video before they broke up, because she had to put it in edit that it was her ex, and I don’t think she wanted to disclose to much information
submitted by Dangsta_03 to GusAndEddy [link] [comments]
2021.10.26 23:57 dealzforyou25 60% Off ALLcool 4.5Q Air Fryer with Classic Timer and Temp Control in Black for $47.99 Original Price: $119.99 Use code: 605LGVAS
2021.10.26 23:57 kingbobbyb5757 Who ever this was I'm not even mad and I want you to see this.
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2021.10.26 23:57 Donnathesinger Any way to combine multiple (fantasy) saves in one file?
I'm pretty sure the answer to this is no, but Simmers always do things that amaze me so I figure can't hurt to ask.
Can you somehow combine multiple saves into one file? Lemme 'splain in case that isn't clear. Eryn with a Y along with other creators redid Willow Creek into New Orleans. Okay I love that and want to play that save. However, then a group of creators got together and redid Sulani and Brindleton Bay. I love those and want to play them. But I want all of this in ONE save. I want to play one save file with all redesigned worlds.
Is this possible? I know I could just upload all the lots to my gallery and add them to one of the other save files, but they have used T.O.O.L. to modify the world/town and that would be lost.
submitted by Donnathesinger to Sims4 [link] [comments]
2021.10.26 23:57 TraditionalGoal422 🐕 Doge Army Token (DGAT) 🐕 | Just launched on PancakeSwap | Weekly Giveaways and Redistribution to Holders | Mission: Rewarding Holders, Helping Dogs and Killing Zeros! 🚀
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DGAT #DogeArmyToken #DogeArmy #DogeCoin submitted by TraditionalGoal422 to SatoshiBets [link] [comments]
2021.10.26 23:57 Human-Ad8941 Bought this high. Am I dumb?
2021.10.26 23:57 nashiemate Should I buy OTW Tomori?
I’m just wondering if I should invest into a Fikayo Tomori OTW card as AC Milan are 4/5 wins for a +1 upgrade. Although their next opponents are Roma, I feel if I buy him now and they win I could make some profit on the card. Although with that being said I’m not the best with buying cards at the right time. Any help would be appreciated. Thanks
submitted by nashiemate to fut [link] [comments]
2021.10.26 23:57 diegolopes9999 Main Line next waves
| So guys, based on the recently rumors from today and the previous ones (Also SKU list from Yakface) I´ve managed to do a tentative list of what I believe will be the next waves for the main Black Series lines.|
Names in Italics means that hasn´t been confirmed officialy by Hasbro, bold means confirmation and promotional images and normal text means pipeline reveals. Also my wave list does not include the confirmed/rumored Deluxe figures since they are not part of any wave.
Please feel free to give your opinion on how do you think the Wave assortments will be.
submitted by diegolopes9999 to starwarsblackseries [link] [comments]
2021.10.26 23:57 carrotcypher Any MMA fans here who would want to sponsor a Shiba Inu MMA event?
I work with Future MMA and we're building the next event and I'm feeling out if this community would be interested in sponsoring an event to have the entire canvas be a big Shiba Inu and give some Shiba Inu to the fighters as well when they fight. Since Shiba Inu coin seems to be fighters, it seemed apt.
submitted by carrotcypher to Shibainucoin [link] [comments]
2021.10.26 23:57 nick_air How do I declare a medical condition?
Right now I'm in BMT. Should I go to the MO first, and ask him to help book an appointment with a doctor at cgh for example, or should I go see a specialist outside first and get them to write a memo for me to pass to the MO?
submitted by nick_air to NationalServiceSG [link] [comments]
2021.10.26 23:57 LargePurpleShoe A Mid Autumn Moon Offering of Dango and Autumn Flowers for Tsukimi Tonight
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2021.10.26 23:57 Yungsosa275 QC check what are we sayin ?
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2021.10.26 23:57 dem0n0cracy The path from pollutants in food to a heightened allergic response — Study in mice suggests cadmium in the gut mimics vitamin D deficiency
The path from pollutants in food to a heightened allergic response Study in mice suggests cadmium in the gut mimics vitamin D deficiency
Peer-Reviewed Publication OHIO STATE UNIVERSITY
PrintEmail App COLUMBUS, Ohio – Exposure to the heavy metal cadmium is known to irritate the stomach and lungs or cause kidney disease, but new research links another health issue to inadvertently ingesting low doses of the pollutant: high activation of the antibodies that cause an allergic response.
Researchers traced this link in mice to gut bacteria that, after exposure to ingested cadmium, over-produced an enzyme that degrades vitamin D – effectively creating conditions that mimic vitamin D deficiency. In terms of clinical effects, the mice sensitized to a specific allergen that consumed cadmium produced high levels of antibodies against the allergen as well as immune cells that increased their respiratory symptoms.
Separate epidemiological research has shown an association in children between vitamin D deficiency and higher susceptibility to asthma and other allergy symptoms. And a Congressional report released on Sept. 29 disclosed an unexpected source of cadmium in kids, announcing that dangerous levels of toxic heavy metals, including cadmium, had been detected in several brands of baby food.
“The problem is, because cadmium doesn’t degrade easily – it has a half-life in the body of at least 15 years – if you are chronically exposed to low doses, it accumulates over time,” said Prosper Boyaka, professor and chair of veterinary biosciences at The Ohio State University and senior author of the study. “It’s also not something we can easily avoid being exposed to because it can remain in air, soil and water.”
Most people ingest the natural element cadmium, a heavy metal used for batteries and making pigments, by eating plant and animal foods that have absorbed the pollutant or drinking contaminated water. The Environmental Protection Agency lists cadmium among eight metals considered extremely toxic at small concentrations.
Boyaka and colleagues found that an experimental compound that inhibits the activated enzymes reduced the allergic response in mice that ingested cadmium.
“We proposed two possible strategies in the paper,” Boyaka said. “One is vitamin D supplementation, but that has to happen before cadmium exposure has caused a heightened allergic reaction, so the question would be when to use a supplement. We also propose targeting those enzymes as a way to prevent the heightened allergic response.”
The research was published recently in the journal Mucosal Immunology.
Environmental pollutants such as cadmium and lead are considered contributors – along with genetic predisposition and overuse of antibiotics – to the growing number of people with allergies, but the mechanisms behind that association aren’t well-understood, Boyaka said.
In this study, researchers added what is considered a “subtoxic” dose of cadmium to drinking water consumed by groups of mice for 28 days. Using a mouse model that simulates human genetic predisposition to an egg allergy, the team exposed the mice to an egg protein to test their allergic response.
Mice that drank water containing subtoxic doses of cadmium and then were exposed to the allergen had a stronger allergic reaction – in the form of internal inflammatory actions and allergy symptoms – than the response in control mice.
“Our hypothesis was that cadmium would change the microbe population in the gut because we know that dysbiosis, or a change in the microbiota, can drive allergic responses. And yes, giving those tiny, tiny doses of cadmium in the drinking water did change allergic sensitization,” Boyaka said.
The effect was known to occur in the gut, as expected, because germ-free mice, which lack intestinal microbes, that were orally exposed to cadmium did not over-produce the antibody that causes an allergic response. But the researchers determined the cadmium wasn’t killing cells or making the intestines leaky. A series of experiments linked cadmium in the gut to production of inflammatory molecules – as well as to stimulation of the two enzymes that degrade vitamin D.
“That’s the main finding – after exposure to subtoxic doses of heavy metals, the pollutants remain in soft tissue, including in the gut. And what they do is make cells more reactive. In the gut, specifically, bacteria will make certain cells produce more of the enzyme that degrades vitamin D,” Boyaka said. “That’s a connection that we did not know before.”
Boyaka’s lab is now investigating potential compounds that could be used to block the vitamin D-degrading enzymes.
This work was supported by grants from the National Institutes of Health and the National Center for Advancing Translational Sciences. The researchers conducted experiments using the Ohio State Center for Clinical and Translational Science Mass Spectrometry and Proteomics Core.
Co-authors, all from Ohio State, include Eunsoo Kim, Astrid Bonnegarde-Bernard, Stephen Opiyo, Marisa Joldrichsen, Zayed Attia, Brian Ahmer and Estelle Cormet-Boyaka.
submitted by dem0n0cracy to ketoscience [link] [comments]